The Dusk has affected this world several times and is now on the verge of ruin. In the western reaches of the Land of Dusk, there exists a nation that has prospered through its use of alchemy. In order to survive the inevitable arrival of being swallowed by the Dusk, people devote efforts into rediscovering the relics of past alchemy. Research on alchemy of previous eras is conducted in a place called "Central City," with the goal to rediscover techniques in order to halt the Dusk's progression. In this small town on the outskirts called "Colseit," two alchemists whose knowledge on the old and new age of alchemy cross paths. The girl's name is Escha. Her synthesis skills with the cauldron comes from her late mother and dedicated her life to serve the community she grew up in with dreams from skies above. The boy's name is Logy. His imbuing knowledge comes from his studies from Central City and currently seeks to live in different working conditions due to unfulfilled dreams in the city. After being assigned to the Colseit branch's Research & Development team, these two alchemists meet. As they send their dreams up into the Dusk Sky, these two work together to carry out assignments using their alchemy skills and to investigate relics, which leads to new knowledge tied between stories of the past and present.